Speeding up sustainable solution-phase peptide synthesis using T3P® as a green coupling reagent: methods and challenges

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چکیده

A fast and greensolution-phase peptide synthesis (GSolPPS) via continuous protocol, addressed with propylphosphonic anhydride T3P® as coupling reagent N -benzyloxycarbonyl-protecting group easily removed by hydrogenation is herein reported.

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ژورنال

عنوان ژورنال: Green Chemistry

سال: 2023

ISSN: ['1463-9262', '1463-9270']

DOI: https://doi.org/10.1039/d3gc00431g